Tuesday, November 9, 2010

True Blood (Out Of Skin)

Canadian scientists have cooked up a way to convert skin cells into blood cells and then grow them, meaning patients could provide their own blood type for transfusions.

Skin cells that are removed from the patient can be multiplied in a petri dish and converted into a large quantity of blood cells, which themselves can be multiplied, lead researcher Mick Bhatia told CNN.


"We're hoping that about a 4-by-3-centimeters patch of skin could be removed from the patient, be converted through this process, which we clearly have to optimize, and ultimately have enough to transplant (enough blood for) a full-grown adult," said Bhatia, scientific director of the Stem Cell and Cancer Research Institute in McMaster's Michael G. DeGroote School of Medicine.

The scientists were able to convert the cells directly without first converting them to pluripotent stem cells - the kind that can grow into any type of organ or tissue - and then converting them again to blood, Bhatia said.

"This groundbreaking work from Mick Bhatia's lab is both fascinating and important," said Samuel Weiss, professor and director, Hotchkiss Brain Institute, University of Calgary. "It heralds a new age by discovering a role for 'directed differentiation' in the treatment of cancers and other disorders of the blood and immune system."

It's going to be years before this procedure can be used of course, but the fact that it can work is an exciting development that may soon be able to save lives.

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