17-Year-Old Designs Cancer Breakthrough

Younger than most high school graduates, Angela Zhang has won a $100,000 prize in the Siemens Competition in Math, Science & Technology for a breakthrough that has several applications in medicine, but most notably in treatment of cancer.

Her creation is being heralded as a “Swiss army knife of cancer treatment.” Zhang managed to develop a nanoparticle that can be delivered to the site of a tumor through the drug salinomycin. Once there it kills the cancer stem cells. However, Zhang went further and included both gold and iron-oxide components, which allow for non-invasive imaging of the site through MRI and Photoacoustics.

As to why she chose this as her project, Zhang explains that she was surprised when looking at the survival rates of patients receiving cancer treatment. As cancer stem cells are resistant to many forms of cancer treatment, it seemed like an area worth focusing on. Her nanoparticle is award-winning due to the fact it has the potential to overcome cancer resistance while offering up the ability to monitor the effects of the treatment in real-time using existing imaging techniques.

Zhang’s achievement is impressive considering she is only 17 years old, but also due to the level of understanding required to create such a nanoparticle in the first place. She has spent over 1,000 hours since 2009 researching and developing the particle, and wants to go on to study chemical engineering, biomedical engineering, or physics. Her dream job is to be a research professor.